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You can get a range of similar yeast infection medications without a prescription, too. Others are suppositories or vaginal tablets you place in your. vaginal candidiasis is a type of yeast infection in the vagina that is caused by the. many women often mistakenly think they have a yeast infection and treat themselves, when they actually have a similar vaginal infection that will not respond to self-treatment with over-the-counter yeast-fighting medications. A study by the american social health association found that most women self-treated vaginal infections before calling a health care professional. over-the-counter suppository medications can usually treat vaginal yeast infections. Application yeast infection treatments come in multiple forms, including oral, suppository, and topical creams. Yeast infection treatments can be taken either orally or vaginally and they tend to have the same success rate, says dr. The vaginal treatment can be for one, three, or seven days depending on the severity of your. Many yeast infection treatments come in 1-day, 3-day, and 7-day strengths. Over-the-counter vaginal creams and other products you can buy often have the same ingredients to fight a yeast infection. Look for otc yeast infection medications ending in azole, miconazole, clotrimazole. Brandye says these are easily accessible and will treat a yeast infection.